One of the focal points of research at the Chair for Applied Microbiology is antibacterial strategies. Novel antibiotics are urgently needed to face the rising number of infections with multi-resistant bacterial pathogens.  The antimicrobial potential of Streptomycetes as producers of natural compounds has been successfully used to treat bacterial infections since the very beginning of antibiotic therapy. One focus is therefore the search for novel antibiotic classes from natural sources. Additionally, other compounds of natural, synthetic, or semi-synthetic origin are analysed within this research group. Using mass spectrometry-based techniques, we analyse the modes of action and targets of novel antimicrobial compounds. The expertise in unravelling the mode of action of novel compounds has been used for many years in fruitful national and international collaborations with academic and industry partners.

Present Projects

Former Projects